Issue:
The proposed feasibility study is a critical assessment whether an epidemiological study designed to quantify health risks among nuclear workers in Ontario could be conducted in Canada. A feasubility study is needed to determine the appropriate study design, subject recruitment, dose estimation, samples size required, and costs.
Objectives:
The purpose of this study is to conduct a preliminary design and feasibility analysis for a future full epidemiological study designed to quantify health risks among those nuclear workers in Ontario who have been exposed to ionizing radiation from internal emitters. Depending on the outcome of the feasibility study, the full study could be a case-cohort or a cased-control study nested within relevant worker populations.
Anticipated Results:
The main intended outcome of the proposed feasibility study is a critical assessment of whether an epidemiological study designed to quantify health risks among nuclear workers in Ontario could be conducted in Canada. Specifically, data from the current feasibility study will be used to determine the appropriate study design, subject recruitment, dose estimation, samples size required, and costs.
Investigators:
Loraine D. Marrett (Cancer Care Ontario), Minh T. Do, Elisabeth Cardis (Center for Research in Environmental Epidemiology [CREAL]), John R. McLaughlin (Cancer Care Ontario)
